Net clinical benefit of anticoagulation therapy in the elderly patients with atrial fibrillation
نویسندگان
چکیده
منابع مشابه
Net clinical benefit of warfarin therapy in elderly Chinese patients with atrial fibrillation.
BACKGROUND Little is known about the net clinical benefit of warfarin therapy in elderly patients with atrial fibrillation. METHODS AND RESULTS We studied 2339 Chinese patients with nonvalvular atrial fibrillation aged≥80 years: 1805 with no antithrombotic therapy and 534 on warfarin therapy. Patients were stratified according to their CHA2DS2-VASc and HAS-BLED score. The primary end point wa...
متن کاملNet Clinical Benefit of Warfarin in Patients With Atrial Fibrillation
Background—Known risk factors for bleeding during anticoagulant treatment are largely the same as those predicting thromboembolic events in patients with atrial fibrillation (AF). Our objective was to investigate how to maximize the likelihood of avoiding both stroke and bleeding. Methods and Results—All 182 678 subjects with atrial fibrillation in the Swedish Hospital Discharge Register were s...
متن کاملEligibility for anticoagulation in elderly patients with atrial fibrillation.
Eligibility for Anticoagulation in Elderly Patients With Atrial Fibrillation To the Editor: Hylek et al concluded in a recent publication that hospitalized elderly patients with atrial fibrillation (AF) may not be optimal candidates for anticoagulation therapy because of their many contraindications.1 However, hospitalized patients enrolled in this study may not be representative of the patient...
متن کاملLiver Cirrhosis in Patients With Atrial Fibrillation: Would Oral Anticoagulation Have a Net Clinical Benefit for Stroke Prevention?
BACKGROUND Patients with liver cirrhosis have been excluded from randomized clinical trials of oral anticoagulation therapy for stroke prevention in atrial fibrillation. We hypothesized that patients with liver cirrhosis would have a positive net clinical benefit for oral anticoagulation when used for stroke prevention in atrial fibrillation. METHODS AND RESULTS This study used the National H...
متن کاملAnticoagulation for atrial fibrillation in the elderly.
Atrial fibrillation is a risk factor for stroke, particularly among elderly patients. Multiple trials have established that antithrombotic therapy decreases stroke risk. Aspirin is associated with a relative risk reduction of about 21% and adjusted-dose warfarin (international normalized ratio 2.0-3.0) is associated with a relative risk reduction of about 68%. Warfarin is more effective than as...
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ژورنال
عنوان ژورنال: Monaldi Archives for Chest Disease
سال: 2018
ISSN: 2532-5264,1122-0643
DOI: 10.4081/monaldi.2018.961